Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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Original article / research
Year : 2018 | Month : August | Volume : 12 | Issue : 8 | Page : OC34 - OC36

Hyponatremia in Patients Admitted with Stroke

Sivakumar Karunanandham, Thamarai Rajappa, Kalavathy Selvaraju

1. Associate Professor, Department of Medicine, Trichy SRM Medical College Hospital and Research Centre, Trichy, Irungalur, Tamil Nadu, India. 2 Associate Professor, Department of Biochemistry, Trichy SRM Medical College Hospital and Research Centre, Trichy, Irungalur, Tamil Nadu, India. 3. Tutor, Department of Biochemistry, Trichy SRM Medical College Hospital and Research Centre, Trichy, Irungalur, Tamil Nadu, India.

Correspondence Address :
Dr. Thamarai Rajappa,
Associate Professor, Department of Biochemistry, Trichy SRM Medical College Hospital and Research Centre, Trichy, Irungalur-621105, Tamil Nadu, India.
E-mail: drthamsiva@gmail.com

Abstract

Introduction: Many studies have focused on association of serum electrolytes with hypertension. In recent years status of serum sodium have established an important role in the distinguishing the two entities of hyponatremia in Cerebrovascular Accidents (CVA).

Aim: To estimate the serum sodium levels and to determine the incidence and aetiology of electrolyte disturbances in patients with newly diagnosed CVA.

Materials and Methods: This was the cross-sectional study conducted at the tertiary care teaching hospital, Trichy. 202 diagnosed stroke patients were evaluated for presence of hyponatremia. The data was analysed using independent t test using SPSS software 21.

Results: Among the 202 CVA patients, 78 patients (38.61%) presented with hyponatremia. Among the 78 patients, 43 (21.28%) were ascertained as Syndrome of Inappropriate Secretion of Antidiuretic Hormone (SIADH), in which ischemic stroke and haemorrhagic stroke were diagnosed in 31 and 12 patients respectively. Fifteen patients (7.42%) had Cerebral Salt Wasting Syndrome (CSWS), in which 5 patients had ischemic stroke and 10 patients had haemorrhagic stroke. A total of 20 (9.90%) cases had hyponatremia with unknown aetiology. The hospital stay of patients with hyponatremic CVA was more than patients with normal serum sodium level (mean 21 days).

Conclusion: This study shows that hyponatremia was observed in 38.61% of stroke patients. Among hyponatremia stroke cases, 21.28 % had SIADH and 7.42% had CSWS. The hospital stay of hyponatremic CVA patients was longer, hence monitoring of serum sodium is absolutely essential in patients admitted with stroke. Close observation and prompt diagnosis are needed to identify the cause of electrolyte disturbance, because their treatments are completely dissimilar.

Keywords

Cerebral salt wasting syndrome, Cerebro vascular accident, Hyponatremia, Stroke, Syndrome of Inappro

How to cite this article :

Sivakumar Karunanandham, Thamarai Rajappa, Kalavathy Selvaraju. HYPONATREMIA IN PATIENTS ADMITTED WITH STROKE. Journal of Clinical and Diagnostic Research [serial online] 2018 August [cited: 2018 Aug 14 ]; 12:OC34-OC36. Available from
http://www.jcdr.net/back_issues.asp?issn=0973-709x&year=2018&month=August&volume=12&issue=8&page=OC34-OC36&id=11954

DOI and Others

DOI: 10.7860/JCDR/2018/36176.11954

Date of Submission: Feb 27, 2018
Date of Peer Review: Apr 17, 2018
Date of Acceptance: May 24, 2018
Date of Publishing: Aug 01, 2018

FINANCIAL OR OTHER COMPETING INTERESTS: NONE.

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