Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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Original article / research
Year : 2018 | Month : August | Volume : 12 | Issue : 8 | Page : NC01 - NC04

Study of Pupil Dilatation Characteristics in Patients from Southern India with a Single Drop of Topical Tropicamide-Phenylephrine

Anupriya Arthur, Satheesh Solomon T Selvin, Haseena Abdulla, Shreya Elsa Regi, Bijesh Yadav, Thomas Kuriakose

1. Assistant Professor, Department of Ophthalmology, Christian Medical College Vellore, Tamil Nadu, India. 2. Associate Professor, Department of Ophthalmology, Christian Medical College Vellore, Tamil Nadu, India. 3. Optometrist in Contact Lens Fellow, Sankara Nethralaya, Chennai Tamil Nadu, India. (Was Affiliated to Christian Medical College, Vellore, Tamil Nadu, India.) 4. Optometrist in GMM Hospital, Mallappally, Pathanamthitta, Kerala, India. (Was Affiliated to Christian Medical College, Vellore, Tamil Nadu, India.) 5. Associate Research Officer, Department of Biostatistics, Christian Medical College, Vellore, Tamil Nadu, India. 6. Professor, Department of Ophthalmology, Christian Medical College, Vellore, Tamil Nadu, India.

Correspondence Address :
Dr. Satheesh Solomon T Selvin,
Schell Eye Hospital; No 1, Arani Road, Vellore-632001, Tamil Nadu, India.
E-mail: ssts@rediffmail.com

Abstract

Introduction: Dilatation of the pupil is essential for eye examinations and procedures, and when the characteristics are known it will help the clinical work flow. Tropicamide-Phenylephrine combination is the most commonly used dilating agent in ophthalmic clinical practice.

Aim: To study the pupil dynamics and properties on dilatation with Tropicamide (0.8%) + Phenylephrine (5%) combination drops.

Materials and Methods: This was a cross sectional observational study conducted on 132 eyes (right eye) from 132 patients. Baseline measurement of the pupil and pupil dynamics were noted after dilatation with a single drop of Tropicamide-Phenylephrine (5%). Pupil Diameter was measured with Optical Biometer at every 2 minutes till 44 minutes or till the patient achieved full dilatation. Data was analysed using t-test, Mann-Whitney U test and ANOVA was used to compare data between groups.

Results: The average onset of dilatation in our study population was at 9.025.2 minutes (2 to 24 min) from the time of instillation of drops. The mean time taken for full dilatation was 33.025.09 minutes (22 to 42 min) with mean amplitude of 2.390.68 mm (0.9 to 4.2 mm). The rate of dilatation of the pupil was 0.07 0.022 mm/sec (0.03 to 0.14 mm/min). A 98.4% of patients maximally dilated in an average time of 33.03 minutes.

Conclusion: Instillation of a single drop of Tropicamide-Phenylephrine combination drop was effective and provides adequate dilatation for all ophthalmological clinical situations.

Keywords

Optical biometer, Pharmacological dilatation, Pupil dynamics

How to cite this article :

Anupriya Arthur, Satheesh Solomon T Selvin, Haseena Abdulla, Shreya Elsa Regi, Bijesh Yadav, Thomas Kuriakose. STUDY OF PUPIL DILATATION CHARACTERISTICS IN PATIENTS FROM SOUTHERN INDIA WITH A SINGLE DROP OF TOPICAL TROPICAMIDE-PHENYLEPHRINE. Journal of Clinical and Diagnostic Research [serial online] 2018 August [cited: 2018 Jul 18 ]; 12:NC01-NC04. Available from
http://www.jcdr.net/back_issues.asp?issn=0973-709x&year=2018&month=August&volume=12&issue=8&page=NC01-NC04&id=11858

DOI and Others

DOI: 10.7860/JCDR/2018/35115.11858

Date of Submission: Dec 11, 2017
Date of Peer Review: Feb 15, 2018
Date of Acceptance: Apr 27, 2018
Date of Publishing: Aug 01, 2018

FINANCIAL OR OTHER COMPETING INTERESTS: None.

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