Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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Year : 2017 | Month : September | Volume : 11 | Issue : 9 | Page : SR01 - SR02

Autoimmune Haemolytic Anaemia-A Spectrum of Presentation in Children

Amitabh Singh, Anirban Mandal, Ankita Patel, Sataroopa Mishra

1. Assistant Professor, Department of Paediatrics, Chacha Nehru Bal Chikitsalaya, New Delhi, India. 2. Attending Consultant, Department of Paediatrics, Sitaram Bhartia Institute of Science and Research, New Delhi, India. 3. Senior Resident, Department of Paediatrics, Chacha Nehru Bal Chikitsalaya, New Delhi, India. 4. Senior Resident, Department of Paediatrics, Chacha Nehru Bal Chikitsalaya, New Delhi, India.

Correspondence Address :
Dr. Amitabh Singh,
4614, Sector B, Pocket 5 and 6, Vasant Kunj, New Delhi-110070, India.
E-mail: dramit_amy@yahoo.co.in

Abstract

Autoimmune Haemolytic Anaemias (AIHAs) are rare in children. They can be either a primary disease or secondary to/triggered by a host of other clinical conditions. We present five interesting cases of paediatric AIHA associated with infections (viral, bacterial and atypical) and autoimmune diseases {Systemic Lupus Erythematosus (SLE) and Autoimmune Hepatitis (AIH)}. The H1N1 influenza associated AIHA responded to oseltamivir and Intravenous Immunognobulin (IvIg) while the cases secondary to Mycoplasma pneumoniae and pneumococcal bacteraemia required only treatment of the primary infection. AIHA with SLE responded well to corticosteroid therapy but the patient with AIH and AIHA succumbed to severe liver failure. Rest of the four cases with good response to therapy did not have any recurrence/relapse of AIHA during their follow up periods.

Keywords

Autoimmune hemolysis, Autoimmune hepatitis, Mycoplasma pneumoniae, Systemic lupus erythematosus

How to cite this article :

Amitabh Singh, Anirban Mandal, Ankita Patel, Sataroopa Mishra. AUTOIMMUNE HAEMOLYTIC ANAEMIA-A SPECTRUM OF PRESENTATION IN CHILDREN. Journal of Clinical and Diagnostic Research [serial online] 2017 September [cited: 2018 Jan 19 ]; 11:SR01-SR02. Available from
http://www.jcdr.net/back_issues.asp?issn=0973-709x&year=2017&month=September&volume=11&issue=9&page=SR01-SR02&id=10646

DOI and Others

DOI: 10.7860/JCDR/2017/27895.10646

Date of Submission: Feb 26, 2017
Date of Peer Review: May 26, 2017
Date of Acceptance: May 29, 2017
Date of Publishing: Sep 01, 2017

FINANCIAL OR OTHER COMPETING INTERESTS: None.

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