Congenital Adrenal Hyperplasia– A Rare Cause of Central Precocious Puberty—A Case ReportCorrespondence Address :
Dr. Jaydeep Majumdar,
House No. 4/24, Viveknagar, Kolkata-700075, India.
The term ‘Precocious puberty’ refers to the appearance of pubertal signs at an earlier age than established standard. Precocious puberty may be central or peripheral. Central precocious puberty is caused by early maturation of hypothalamic-pituitary-gonadal axis. Peripheral precocious puberty is due to inappropriate secretion of sex steroid hormones from adrenal gland or gonad or from exogenous source and does not involve hypothalamo-pituitary-gonadal axis. We report a rare case where inspite of clinical and hormonal evidence of central precocious puberty ultimately an adrenal pathology was established in a six-year-old boy.
Encephalitis, Hypothalamo-pituitary-gonadal axis, Sex steroid
Jaydeep Majumdar, Abhijeet Sharan, Sarmishtha Mukhopadhyay, Bhaskar Ghosh, Sarbani Sengupta. CONGENITAL ADRENAL HYPERPLASIA– A RARE CAUSE OF CENTRAL PRECOCIOUS PUBERTY—A CASE REPORT. Journal of Clinical and Diagnostic Research [serial online] 2017 November [cited: 2018 Jan 20 ]; 11:SD01-SD03. Available from
Date of Submission: Feb 16, 2017
Date of Peer Review: May 13, 2017
Date of Acceptance: Sep 04, 2017
Date of Publishing: Nov 01, 2017
FINANCIAL OR OTHER COMPETING INTERESTS: None.
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