Prosthetic Joint Infection due to Burkholderia cenocepacia: An Opportunistic Pathogen with an Expanding Spectrum of DiseaseCorrespondence Address :
Dr. Benu Dhawan,
Room No. 2075, Department of Microbiology, All India Institute of Medical Sciences, Ansari Nagar-110029, Delhi, India.
Burkholderia cenocepacia is an opportunistic pathogen widespread in moist environments. It has been associated with lung infections, blood, skin and genitourinary tract infections. We report here the first case of Prosthetic Joint Infection (PJI) caused by B. cenocepacia isolated from the periprosthetic tissue samples and prosthesis sonicate fluid identified by Matrix-Assisted Laser Desorption Ionization-Time-of-Flight Mass Spectrometry (MALDI-TOF MS). A good clinical outcome was obtained by two-stage exchange arthroplasty and administration of co-trimoxazole and ciprofloxacin. In addition to the expanding spectrum of this opportunistic pathogen, this case also shows the reliability of newer diagnostic tools to rapidly identify the Burkholderia Cepacia Complex (BCC) to the species level.
Burkholderia cepacia complex, Mass spectrometry, Periprosthetic tissue
Sujeesh Sebastian, Rajesh Malhotra, Rojaleen Das, Arti Kapil, Benu Dhawan. PROSTHETIC JOINT INFECTION DUE TO BURKHOLDERIA CENOCEPACIA: AN OPPORTUNISTIC PATHOGEN WITH AN EXPANDING SPECTRUM OF DISEASE. Journal of Clinical and Diagnostic Research [serial online] 2017 November [cited: 2018 Jan 20 ]; 11:DD05-DD07. Available from
Date of Submission: Sep 01, 2017
Date of Peer Review: Sep 19, 2017
Date of Acceptance: Oct 07, 2017
Date of Publishing: Nov 01, 2017
FINANCIAL OR OTHER COMPETING INTERESTS: None.
- Emerging Sources Citation Index (Web of Science, thomsonreuters)
- Index Copernicus ICV 2016: 132.37
- Academic Search Complete Database
- Directory of Open Access Journals (DOAJ)
- Embase & EMbiology
- Google Scholar
- HINARI Access to Research in Health Programme
- Indian Science Abstracts (ISA)
- Journal seek Database
- Popline (reproductive health literature)