Anaesthetic Considerations in Patients of Takayasu Arteritis and Blunting of Stress Response to Intubation by Dexmedetomidine Infusion “A Report of two Cases”Correspondence Address :
Dr. Deepak Dwivedi,
Department of Anaesthesia and Critical Care, Institute of Naval Medicine, INHS Asvini,
Colaba, Mumbai-400005, Maharashtra, India.
Takayasu arteritis is an entity resulting in pan-endarteritis. It involves the principal arteries resulting in ischaemia and persistent hypertension. Hypertension affects the anaesthetic management where the principal goal is to control the haemodynamic stability during the induction and for the entire course of anaesthesia preventing damage to the end organs. We present two cases, one paediatric with hypertension refractory to medical management posted for nephrectomy and one adult patient posted for diagnostic hysterolaparoscopy. Both the cases were administered dexmedetomidine, an alpha 2 agonist during the pre-induction period. Sympatholysis caused by infusion dexmedetomidine was effectively utilized in both the cases hence, pre-induction infusion of dexmedetomidine can be utilized to obtund the haemodynamic response to intubation.
Adrenergic alpha 2 agonist, Hypertension, Nephrectomy, Paediatric, Vasculitis
Deepak Dwivedi, Kiran Sheshadri, Abhijit Karmarkar, Arijit Ray, Swayam Tara. ANAESTHETIC CONSIDERATIONS IN PATIENTS OF TAKAYASU ARTERITIS AND BLUNTING OF STRESS RESPONSE TO INTUBATION BY DEXMEDETOMIDINE INFUSION “A REPORT OF TWO CASES”. Journal of Clinical and Diagnostic Research [serial online] 2017 October [cited: 2018 Jan 23 ]; 11:UD01-UD03. Available from
Date of Submission: Apr 05, 2017
Date of Peer Review: May 19, 2017
Date of Acceptance: Aug 11, 2017
Date of Publishing: Oct 01, 2017
FINANCIAL OR OTHER COMPETING INTERESTS: None.
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