Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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Year : 2017 | Month : October | Volume : 11 | Issue : 10 | Page : KE01 - KE06

Marine-Derived Bioactive Peptides with Pharmacological Activities- A Review

Sana Rabiei, Mehdi Nikoo, Masoud Rezaei, Mahmoud RaFIeian Kopaei

1. PhD Student, Department of Seafood Science, Faculty of Marine Sciences, Tarbiat Modares University, Noor, Iran. 2. Assistant Professor, Artemia and Urmia Lake Research Institute, Urmia University, Urmia, Iran. 3. Professor, Department of Seafood Science, Faculty of Marine Sciences, Tarbiat Modares University, Noor, Iran. 4. Professor, Medical Plants Research Center, Basic Health Sciences Institute, Shahrekord University of Medical Sciences, Shahrekord, Iran.

Correspondence Address :
Dr. Mahmoud Ra?eian-Kopaei,
Professor, Medical Plants Research Center, Basic Health Sciences Institute,
Shahrekord University of Medical Sciences, Shahrekord, Iran.
E-mail: rafieian@yahoo.com

Abstract

Some nutritional factors are related to chronic disease. In response to increased concern regarding nutrition and health, the functional and nutraceuticals food markets have been developed. During food digestion, proteins are hydrolyzed and a wide range of peptides are formed. Some of these peptides have special structures which permit them to confer particular biological functions. Marine animals which involve more than half of the world biological varieties are a wide source of bioactive proteins and peptides. Marine derived peptides show various physiologic functions such as anti-oxidant, antimicrobial, anti-cancer, Angiotensin-1-Converting Enzyme (ACE) glucosidase and a-amylase inhibitory effects in vitro. Before application of marine bioactive peptides as nutraceuticals or functional food ingredients, their efficacy should be approved through pre-clinical animal and then clinical studies. The aim of this study was to review the studies conducted on the pharmacological effect of marine bioactive peptides in animal models and humans.

Keywords

Chronic disease, Pharmaceutical effect, Therapeutic properties

How to cite this article :

Sana Rabiei, Mehdi Nikoo, Masoud Rezaei, Mahmoud RaFIeian Kopaei. MARINE-DERIVED BIOACTIVE PEPTIDES WITH PHARMACOLOGICAL ACTIVITIES- A REVIEW. Journal of Clinical and Diagnostic Research [serial online] 2017 October [cited: 2018 Jan 20 ]; 11:KE01-KE06. Available from
http://www.jcdr.net/back_issues.asp?issn=0973-709x&year=2017&month=October&volume=11&issue=10&page=KE01-KE06&id=10753

DOI and Others

DOI: 10.7860/JCDR/2017/28672.10753

Date of Submission: Mar 22, 2017
Date of Peer Review: Jun 08, 2017
Date of Acceptance: Jul 13, 2017
Date of Publishing: Oct 01, 2017

FINANCIAL OR OTHER COMPETING INTERESTS: None.

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