Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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Case report
Year : 2017 | Month : March | Volume : 11 | Issue : 3 | Page : ZD16 - ZD18

Basaloid Squamous Cell Carcinoma of Tongue: A Report with Emphasis on Immunohistochemistry

Karuna Kumari, Vanishree C Haragannavar, K Vineeth Kumar, Kavitha Prasad, Shwetha Nambiar

1. Postgraduate Student, Department of Oral Pathology and Microbiology, Faculty of Dental Sciences, M.S. Ramaiah University of Applied Sciences, Bengaluru, Karnataka, India. 2. Assistant Professor, Department of Oral Pathology and Microbiology, Faculty of Dental Sciences, M.S. Ramaiah University of Applied Sciences, Bengaluru, Karnataka, India. 3. Associate Professor, Department Oral and Maxillofacial Surgery, Faculty of Dental Sciences, M.S. Ramaiah University of Applied Sciences, Bengaluru, Karnataka, India. 4. Professor and Head, Department of Oral and Maxillofacial Surgery, Faculty of Dental Sciences, M.S. Ramaiah University of Applied Sciences, Bengaluru, Karnataka, India. 5. Tutor, Department of Oral Pathology and Microbiology, Faculty of Dental Sciences, M.S. Ramaiah University of Applied Sciences, Bengaluru, Karnataka, India.

Correspondence Address :
Dr. Karuna Kumari,
Postgraduate Student, Department of Oral Pathology, Faculty of Dental Sciences,
M.S. Ramaiah University of Applied Sciences,
Msr Nagar, Bengaluru-560054, Karnataka, India.
E-mail: karuna2202@gmail.com

Abstract

Basaloid Squamous Cell Carcinoma (BScc ) is a rare entity with its histopathological distinction from conventional squamous cell carcinoma. It is frequently considered a high-grade carcinoma with poor prognosis because of higher rate of distant metastases. Here by, we are reporting a case of 39-year-old male with an ulcer on the left lateral border of the tongue since a month. Histopathological examination of incisional biopsy revealed basaloid tumour cell islands accompanied by component of well differentiated squamous cell carcinoma. To reconfirm this incidental finding immunohistochemistry was carried out for Proliferative Cell Nuclear Antigen (PCNA) and pancytokeratin (AE1/AE3) which was positive to conclude diagnosis of BScc . Further p16 staining was done to rule out Human Papilloma Virus (HPV) infection.

Keywords

Distant metastasis, Human papilloma virus, Proliferative cell nuclear antigen

How to cite this article :

Karuna Kumari, Vanishree C Haragannavar, K Vineeth Kumar, Kavitha Prasad, Shwetha Nambiar. BASALOID SQUAMOUS CELL CARCINOMA OF TONGUE: A REPORT WITH EMPHASIS ON IMMUNOHISTOCHEMISTRY. Journal of Clinical and Diagnostic Research [serial online] 2017 March [cited: 2017 Mar 28 ]; 11:ZD16-ZD18. Available from
http://www.jcdr.net/back_issues.asp?issn=0973-709x&year=2017&month=March&volume=11&issue=3&page=ZD16-ZD18&id=9539

DOI and Others

DOI: 10.7860/JCDR/2017/24308.9539



Date of Submission: Sep 21, 2016
Date of Peer Review: Nov 04, 2016
Date of Acceptance: Nov 29, 2016
Date of Publishing: Mar 01, 2017


Financial OR OTHER COMPETING INTERESTS: None.

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