Light Chain Myeloma induced Severe HypertriglyceridemiaCorrespondence Address :
Dr. Prabhat Kumar,
Senior Resident, Department of Medicine, OPD Block, PGIMER and Dr Ram Manohar Lohia Hospital, New Delhi, India.
Hyperlipidemia is very common in general population and incidence has further increased in recent years. Evaluation of patient presenting with lipid disorders is essential to obtain a definite diagnosis to prevent complications, and apply the most appropriate treatment. An isolated elevation in triglyceride levels may be caused by a primary disorder of lipid metabolism like familial hypertriglyceridemia. It may also arise secondary to a number of conditions like diabetes mellitus, alcohol intake, hypothyroidism, drugs, infections and nephrotic syndrome. Herein, we describe a case of secondary hypertriglyceridemia leading to Nonalcoholic Steatohepatitis (NASH) in a young female which was attributed to Multiple Myeloma (MM). Significant reduction in triglyceride levels after starting anti-myeloma therapy established their relation. This is the first case of light chain myeloma causing severe secondary hypertriglyceridemia.
Hyperlipidemic myeloma, Lipoprotein lipase, Multiple myeloma, Nonalcoholic steatohepatitis
Shafeeque Rahman, Prabhat Kumar, Subodh Kumar Mahto, Rajinder Singh Tonk, Rajesh S Taneja. LIGHT CHAIN MYELOMA INDUCED SEVERE HYPERTRIGLYCERIDEMIA. Journal of Clinical and Diagnostic Research [serial online] 2017 March [cited: 2017 May 28 ]; 11:OD01-OD03. Available from
Date of Submission: Sep 28, 2016
Date of Peer Review: Dec 01, 2016
Date of Acceptance: Dec 01, 2016
Date of Publishing: Mar 01, 2017
Financial OR OTHER COMPETING INTERESTS: None.
- PubMed Central® (PMC)New
- Academic Search Complete Database
- Chemical Abstracts Service
- Directory of Open Access Journals (DOAJ)
- Embase & EMbiology
- Google Scholar
- HINARI Access to Research in Health Programme
- Indian Science Abstracts (ISA)
- Journal seek Database
- Open J-Gate
- Popline (reproductive health literature)