Bladder Adenocarcinoma: A Persisting Diagnostic DilemmaCorrespondence Address :
Dr. Arijit Bishnu,
Assistant Professor, Department of Pathology, Manipal Medical College, Manipal-576104, Karnataka, India.
Primary urinary Bladder Adenocarcinoma (PBA) is an uncommon neoplasm and can cause diagnostic difficulties due to histologic similarities with adenocarcinomas of adjacent structures like Gastrointestinal Tract (GIT) and prostate, since involvement of the bladder by metastasis or direct spread can occur. Seven cases of bladder adenocarcinomas were diagnosed during a period of four years in a tertiary care hospital. Patient’s age ranged from 26-78 years with a male predilection. Three cases were signet ring type adenocarcinomas, two cases were subtyped as enteric variant, one as mucinous variant and one as adenocarcinoma Not Otherwise Specified (NOS) variant. One case showed urachal involvement. Common site of involvement was the base and posterior wall of the bladder. Three cases had prior history of GIT malignancy. No morphologic difference was identified to differentiate primary from secondary adenocarcinomas. Bladder adenocarcinoma is rare tumours. Primary and secondary adenocarcinomas cannot be distinguished from each other on morphologic grounds. Ancillary studies may have limited role in distinguishing between the two. Hence, clinical correlation has a major role in their evaluation.
Primary and secondary adenocarcinomas, Tumour, Urachal
Geetha Vasudevanevan, Arijit Bishnu, Brij Mohan Kumar Singh, DeepakDeepak Nayak M, Pooja Jain. BLADDER ADENOCARCINOMA: A PERSISTING DIAGNOSTIC DILEMMA. Journal of Clinical and Diagnostic Research [serial online] 2017 March [cited: 2017 Mar 28 ]; 11:ER01-ER04. Available from
Date of Submission: Oct 04, 2016
Date of Peer Review: Nov 16, 2016
Date of Acceptance: Jan 18, 2017
Date of Publishing: Mar 01, 2017
Financial OR OTHER COMPETING INTERESTS: None.
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