Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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Original article / research
Year : 2017 | Month : August | Volume : 11 | Issue : 8 | Page : AC01 - AC03

Histogenesis of Muscularis Mucosa and Muscularis Externa of Stomach: A Human Foetal Study

Babita Pangtey, Jagat Mohini Kaul, Sabita Mishra

1. Assistant Professor, Department of Anatomy, MAMC, Delhi, India. 2. Director Professor, Department of Anatomy, BSA Medical College, Delhi, India. 3. Director Professor, Department of Anatomy, MAMC, Delhi, India.

Correspondence Address :
Dr. Sabita Mishra,
Director Professor, Department of Anatomy, MAMC, Delhi-110002, India.
E-mail: sabitamishra12@gmail.com

Abstract

Introduction: The histological and developmental knowledge of musculature of stomach wall is vital for the assessment and management of various associated congenital abnormalities like hypertrophy of pyloric musculature and pathologies of nerve terminals and ganglia.

Aim: To study the development of muscularis mucosa and muscularis externa in human foetal stomach.

Materials and Methods: The study was conducted on 22 aborted human foetuses of varying gestational ages ranging from 10-26 weeks. The foetuses were procured after obtaining Institutional Ethical Clearance and informed consent of parents of the aborted foetuses. Stomach was dissected and immersed fixed in 10% formalin and then sectioned and stained with Haematoxylin and Eosin and Massonís Trichrome.

Results: The muscularis mucosa appeared as a thin layer of smooth muscle strands at 14 weeks of gestation and later developed as a continuous and well developed layer by 22 weeks. Muscularis externa was composed of only two layers in early gestational ages from 10-15 weeks with predominant circular and discrete outer longitudinal muscle coat. The innermost layer of oblique muscle developed later at 16 weeks of gestation.

Conclusion: The gastric muscularis mucosa and muscularis externa developed and differentiated sequentially in the human foetuses. The musculature in pyloric region of stomach was more developed and thick than the body and fundus of stomach in all foetuses at all gestational ages.

Keywords

Development, Gestational age, Massonís trichrome

How to cite this article :

Babita Pangtey, Jagat Mohini Kaul, Sabita Mishra. HISTOGENESIS OF MUSCULARIS MUCOSA AND MUSCULARIS EXTERNA OF STOMACH: A HUMAN FOETAL STUDY. Journal of Clinical and Diagnostic Research [serial online] 2017 August [cited: 2017 Aug 22 ]; 11:AC01-AC03. Available from
http://www.jcdr.net/back_issues.asp?issn=0973-709x&year=2017&month=August&volume=11&issue=8&page=AC01-AC03&id=10323

DOI and Others

DOI: 10.7860/JCDR/2017/26219.10323

Date of Submission: Dec 21, 2016
Date of Peer Review: Feb 22, 2017
Date of Acceptance: Apr 17, 2017
Date of Publishing: Aug 01, 2017

Financial OR OTHER COMPETING INTERESTS: None.

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