Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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Case report
Year : 2017 | Month : April | Volume : 11 | Issue : 4 | Page : UD01 - UD02

Acute Respiratory Distress Syndrome Complicated by Amiodarone Induced Pulmonary Fibrosis: Don’t Let Your Guard Down

Vipin Kumar Singh, Vijeta Maheshwari

1. Assistant Professor, Department of Anaesthesia, King George’s Medical University, Lucknow, Uttar Pradesh, India. 2. Senior Resident, Department of Anaesthesia, King George’s Medical University, Lucknow, Uttar Pradesh, India.

Correspondence Address :
Dr. Vipin Kumar Singh,
Jewel Apartment A-2-2, Jopling Road, Hazratganj, Lucknow-226003, Uttar Pradesh, India.


Amiodarone is an antiarrhythmic agent which is commonly used to treat both supraventricular and ventricular arrhythmias. This iodine containing compound has been associated with several adverse events like it tends to accumulate in several organs. Among those, the most serious is Amiodarone Pulmonary Toxicity (APT). While the incidence of this complication has decreased with the use of lower doses of amiodarone but it can occur with any dose. Pulmonary complications usually present as an acute or subacute pneumonitis. On chest X-ray and high-resolution Computed Tomography (CT), diffuse infiltrates were found. Here, we present a case in which acute respiratory distress syndrome like features were detected which got subsided after stopping tablet amiodarone. The patient was a known case of atrial fibrillation for which she was taking tablet amiodarone for the last six months.


Arrhythmia, Pulmonary toxicity, Upper respiratory tract infection

DOI and Others

DOI: 10.7860/JCDR/2017/24710.9674

Date of Submission: Oct 09, 2016
Date of Peer Review: Oct 31, 2016
Date of Acceptance: Jan 17, 2017
Date of Publishing: Apr 01, 2017


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