Seroprevalence and Trends of Transfusion Transmissible Infections in Blood Donors in Andaman and Nicobar Islands- An Institutional Retrospective StudyCorrespondence Address :
Dr. Rupinder Kaur Brar,
306, Andaman Teal House, Delanipur, Port Blair, Andaman and Nicobar Islands-744102, India.
Introduction: Transfusion Transmissible Infections (TTIs) such as Human Immunodeficiency Virus (HIV), Hepatitis B virus (HBV), Hepatitis C Virus (HCV) and syphilis pose a threat to blood safety in a developing country like India.
Aim: To determine the prevalence of TTIs among healthy donors in Andaman and Nicobar Islands, India, and to further help in determination of the population subset to be focused on for enhancing blood donor pool.
Materials and Methods: This retrospective cross-sectional study was conducted on all voluntary and replacement donors in a tertiary health care centre in Andaman and Nicobar Islands for a period of three years. Donor blood was screened for HIV, HBV, HCV, Syphilis and malarial parasite using rapid kits and ELISA.
Results: Out of 12,118 donors, 97.01% were males and 2.99% were females. 9409 (77.64%) were voluntary donors and 2709 (22.35%) were replacement donors. Majority of the screened donors belonged to 25 to 40 age group. Out of 12,118 donors, 265 (2.18%) were seropositive. Among them, 8 (0.066%) were HIV positive, 15 (0.124%) HCV positive, 128 (1.056%) HBsAg positive, 30 (0.247%) Syphilis positive and 84 (0.693%) were positive for malarial antigen. Yearly prevalence of seropositivity was 2.370%, 2.113% and 2.082% for three consecutive years.
Conclusion: With high prevalence of TTIs among healthy donors, safe blood transfusion is still a challenge in developing countries. This continues to place unacceptable burden on health sector. There is a need for encouragement of voluntary blood donation, strict donor selection criteria and sensitive screening tests to minimize TTIs in Indian setting.
Blood screening, Replacement donors, Voluntary donors
Sahil Sehgal, P.S Shaiji, Rupinder Kaur Brar. SEROPREVALENCE AND TRENDS OF TRANSFUSION TRANSMISSIBLE INFECTIONS IN BLOOD DONORS IN ANDAMAN AND NICOBAR ISLANDS- AN INSTITUTIONAL RETROSPECTIVE STUDY. Journal of Clinical and Diagnostic Research [serial online] 2017 April [cited: 2017 May 25 ]; 11:EC21-EC24. Available from
Date of Submission: Nov 06, 2016
Date of Peer Review: Dec 16, 2016
Date of Acceptance: Jan 09, 2017
Date of Publishing: Apr 01, 2017
Financial OR OTHER COMPETING INTERESTS: None.
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