Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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Original article / research
Year : 2016 | Month : May | Volume : 10 | Issue : 5 | Page : OC27 - OC31

A Study of Compliance to Antiretroviral Therapy among Hiv Infected Patients at a Tertiary Care Hospital in North Karnataka

Ishwar Siddappa Hasabi, Arun Beekanahalli Shivashankarappa, Chandrashekar Kachapur, Ram Suresh Kaulgud

1. Professor and Head of Department, Department of General Medicine, Karnataka Institute of Medical Sciences, Hubli, Karnataka, India. 2. Post Graduate, Department of General Medicine, Karnataka Institute of Medical Sciences, Hubli, Karnataka, India. 3. Assistant Professor, Department of General Medicine, Karnataka Institute of Medical Sciences, Hubli, Karnataka, India. 4. Assistant Professor, Department of General Medicine, Karnataka Institute of Medical Sciences, Hubli, Karnataka, India.

Correspondence Address :
Dr. Arun Beekanahalli Shivashankarappa,
Postgraduate, Department of General Medicine, Karnataka Institute of Medical Sciences, Hubli, Karnataka, India.
E-mail: arunbsmedicine@gmail.com

Abstract

Introduction: Compliance to Antiretroviral Therapy (ART) is a primary determinant of treatment success of HIV-AIDS. Many studies have shown inadequate compliance to ART in the Indian population.

Aim: To assess the compliance to ART among HIV infected patients, to explore the factors affecting compliance and impact of compliance on CD4 count.

Materials and Methods: A cross-sectional study was conducted with 200 adult patients attending ART center, KIMS, Hubli. The patients were randomly selected and compliance to ART over preceding 3 months was assessed. Reasons for non- compliance were assessed among those with inadequate compliance.

Results: Mean age of the study population was 40.079.99 years. The sex ratio was 1.02:1 (M:F). Majority of patients were in WHO stage 1 with treatment, with CD4 count above 500/l. Pulmonary tuberculosis was the most common opportunistic infection. Most of the patients were on long term ART, more than 5 years {81 (40.5%)}. Most of the patients were on ZLN regimen {97 (48.5%)}. Compliance over the preceding 3 months was 94.84 14.93% for ART and 88.9723.75% for opportunistic infection prophylaxis. There was no significant difference in compliance in relation to age group, sex, educational status, residence, religion, habits, HIV status of spouse or child, the regimen of ART and frequency of dosing. The compliance was better among those on long term treatment, i.e., those on treatment for more than 5 years compared to those who started ART in last 1 year (p=0.06). The most common reasons given by patients for non-compliance were going away from home, busy with other work and simply forgot. Better compliance was associated with higher CD4 count.

Conclusion: Compliance to ART was inadequate in the studied population, which is a major obstacle to success of ART.

Keywords

CD4 count, Compliance to medication, HIV-AID

How to cite this article :

Ishwar Siddappa Hasabi, Arun Beekanahalli Shivashankarappa, Chandrashekar Kachapur, Ram Suresh Kaulgud. A STUDY OF COMPLIANCE TO ANTIRETROVIRAL THERAPY AMONG HIV INFECTED PATIENTS AT A TERTIARY CARE HOSPITAL IN NORTH KARNATAKA. Journal of Clinical and Diagnostic Research [serial online] 2016 May [cited: 2018 Jun 24 ]; 10:OC27-OC31. Available from
http://www.jcdr.net/back_issues.asp?issn=0973-709x&year=2016&month=May&volume=10&issue=5&page=OC27-OC31&id=7792

DOI and Others

DOI: 10.7860/JCDR/2016/17948.7792


Date of Submission: Nov 23, 2015
Date of Peer Review: Jan 20, 2016
Date of Acceptance: Feb 09, 2016
Date of Publishing: May 01, 2016

Financial OR OTHER COMPETING INTERESTS: None.

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