Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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Case report
Year : 2016 | Month : May | Volume : 10 | Issue : 5 | Page : ED03 - ED05

A Tumour in Disguise in the Right Palm- Monophasic Synovial Sarcoma

Vasugi Gramani Arumugam, Sandhya Sundaram, Anita Ramesh, Prathiba Duvuru, Srinivasa Rajappa

1. Post Graduate, Department of Pathology, Sri Ramachandra Medical College and Research Institute, Chennai, India. 2. Professor, Department of Pathology, Sri Ramachandra Medical College, Chennai, India. 3. Professor, Department of Oncology, Sri Ramachandra Medical College and Research Institute, Chennai, India. 4. Professor, Department of Pathology, Sri Ramachandra Medical College and Research Institute, Chennai, India. 5. Associate Professor, Department of Orthopedics, Sri Ramachandra Medical College,Chennai, India.

Correspondence Address :
Dr. Sandhya Sundaram,
2A, Abirami Meaddowland, 32 Park Road, Anna Nagar West, Padi, Chennai-600050, India.
E-mail: sandsrid@gmail.com

Abstract

Synovial sarcoma is one of the poorly differentiated malignant soft tissue tumour occuring commonly among young adults in the extremities. We report a 50-year-old female presenting with a soft tissue mass in the right palm. On examination, a single firm and non tender swelling was noticed adjacent to the thenar muscles. Radiology suggested a benign soft tissue lesion. The swelling, clinically thought to be a lipoma, was excised and sent for histopathological examination. Microscopy showed a highly cellular tumour arranged in nests, cords and pseudo glandular pattern separated by dense fibrocollagenous tissue. An interesting and baffling finding was the presence of a distinct mucin vacuole in many of the tumour cells. A diagnosis of soft tissue sarcoma with epithelial features was considered and a panel of immunohistochemical stains done. Tumour cells showed strong positivity for cytokeratin 7, vimentin, EMA & Bcl2. CD 99 and S100 were focally positive. CD 34 and CEA were negative. In view of the above microscopic and immunohistochemical findings, a diagnosis of monophasic synovial sarcoma of epithelial type was rendered. This case is being documented for the rare morphological appearance of mucin vacuoles in a monophasic epithelial type synovial sarcoma.

Keywords

Epithelial type, Malignant soft tissue tumour, Mucin vacuoles

How to cite this article :

Vasugi Gramani Arumugam, Sandhya Sundaram, Anita Ramesh, Prathiba Duvuru, Srinivasa Rajappa. A TUMOUR IN DISGUISE IN THE RIGHT PALM- MONOPHASIC SYNOVIAL SARCOMA. Journal of Clinical and Diagnostic Research [serial online] 2016 May [cited: 2018 Jan 16 ]; 10:ED03-ED05. Available from
http://www.jcdr.net/back_issues.asp?issn=0973-709x&year=2016&month=May&volume=10&issue=5&page=ED03-ED05&id=7748

DOI and Others

DOI: 10.7860/JCDR/2016/11112.7748


Date of Submission: Sep 04, 2014
Date of Peer Review: Jul 20, 2015
Date of Acceptance: Mar 14, 2016
Date of Publishing: May 01, 2016


Financial OR OTHER COMPETING INTERESTS: None.

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