Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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Original article / research
Table of Contents - Year : 2018 | Month : August | Volume : 12 | Issue : 8 | Page : NC01 - NC04

Study of Pupil Dilatation Characteristics in Patients from Southern India with a Single Drop of Topical Tropicamide-Phenylephrine NC01-NC04

Anupriya Arthur, Satheesh Solomon T Selvin, Haseena Abdulla, Shreya Elsa Regi, Bijesh Yadav, Thomas Kuriakose

Correspondence
Dr. Satheesh Solomon T Selvin,
Schell Eye Hospital; No 1, Arani Road, Vellore-632001, Tamil Nadu, India.
E-mail: ssts@rediffmail.com

Introduction: Dilatation of the pupil is essential for eye examinations and procedures, and when the characteristics are known it will help the clinical work flow. Tropicamide-Phenylephrine combination is the most commonly used dilating agent in ophthalmic clinical practice.

Aim: To study the pupil dynamics and properties on dilatation with Tropicamide (0.8%) + Phenylephrine (5%) combination drops.

Materials and Methods: This was a cross sectional observational study conducted on 132 eyes (right eye) from 132 patients. Baseline measurement of the pupil and pupil dynamics were noted after dilatation with a single drop of Tropicamide-Phenylephrine (5%). Pupil Diameter was measured with Optical Biometer at every 2 minutes till 44 minutes or till the patient achieved full dilatation. Data was analysed using t-test, Mann-Whitney U test and ANOVA was used to compare data between groups.

Results: The average onset of dilatation in our study population was at 9.025.2 minutes (2 to 24 min) from the time of instillation of drops. The mean time taken for full dilatation was 33.025.09 minutes (22 to 42 min) with mean amplitude of 2.390.68 mm (0.9 to 4.2 mm). The rate of dilatation of the pupil was 0.07 0.022 mm/sec (0.03 to 0.14 mm/min). A 98.4% of patients maximally dilated in an average time of 33.03 minutes.

Conclusion: Instillation of a single drop of Tropicamide-Phenylephrine combination drop was effective and provides adequate dilatation for all ophthalmological clinical situations.