Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

Users Online : 22710

Case Series
Table of Contents - Year : 2017 | Month : April | Volume : 11 | Issue : 4 | Page : TR01 - TR03

Cloves Syndrome: Severe Neonatal Presentation TR01-TR03

Silvana Acosta, Viviana Torres, Marķa Paulos, Ignacio Cifuentes

Correspondence
Dr. Silvana Acosta,
Cardenal Newman 821, Las Condes, Santiago, Chile.
E-mail: acosta.doctora@gmail.com

Congenital Lipomatous Overgrowth, Vascular Malformations, Epidermal Nevi and Spinal Abnormalities (CLOVES syndrome) is a newly described and rare overgrowth disorder with serious morbidity. The course of this disease is not well understood and few cases have been reported among neonates. Moreover, not all of the signs of this syndrome are present at birth, making a high index of suspicion necessary. We present a cohort of three newborns with CLOVES syndrome who died due to septic and hemodynamic complications directly related to extensive vascular malformations. We discuss the clinical presentation in the neonatal period and propose a clinical classification.