Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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Case report
Table of Contents - Year : 2017 | Month : April | Volume : 11 | Issue : 4 | Page : ED05 - ED07

Oncogenic Osteomalacia: An Approach to Diagnosis with a Case Report ED05-ED07

Biswajit Dey, Debasis Gochhait, Hema Subramanian, Madhusudhanan Ponnusamy

Correspondence
Dr. Debasis Gochhait, Assistant Professor,
Department of Pathology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER),
Puducherry-605006, India.
E-mail: publicationmail@rediffmail.com

Oncogenic osteomalacia, also known as tumour induced osteomalacia, is a rare paraneoplastic syndrome caused by mesenchymal tumours secreting Fibroblast Growth Factor-23 (FGF-23). The characteristic biochemical findings include hypophosphatemia and low 1,25-dihydroxy vitamin D. The differential diagnosis for hypophosphatemia are varied. We present a case of oncogenic osteomalacia in a 29-year-old female, who presented with complaints of generalized diffuse bone pain and walking difficulty for six months duration. Thus, we have discussed the approach to diagnosis in such a case.