The Outcome of Amniocentesis
at 14 Weeks of Gestation
Latika Narang, Alexandra Sawyer, Vaishali Garg, Onome Ogueh
Dr. Latika Narang; 158,Winkworth Road, Banstead,
Surrey; SM7 2QT
Objective: To compare the safety and efficacy of amniocentesis at 14 weeks of gestation with amniocentesis at ≥15 weeks and chorionic villous sampling.
Method: This was a retrospective study of the pregnancy outcome of 299 women who underwent invasive prenatal diagnosis by using amniocentesis at 14 weeks of gestation, amniocentesis at ≥15 weeks of gestation and chorionic villous sampling. We compared the pregnancy outcomes and the complications in the 3 groups by using the Pearsonís χ2 test or the Fisherís exact test.
Results: There was no significant difference between the women who underwent amniocentesis at 14 weeks of gestation and those who underwent amniocentesis at ≥ 15 weeks of gestation or chorionic villous sampling in terms of failed cultures, miscarriage, preterm pre-labour, rupture of membranes, preterm delivery and neonatal respiratory complications (p > 0.05).
Conclusion: Amniocentesis at 14 weeks of gestation is as safe as amniocentesis at ≥ 15 weeks of gestation and chorionic villous sampling.
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