Correspondence
Dr.Stuti Gupta,
Dept. of Pathology, M.L.N.Medical College,
Allahabad,(U.P.), (India).Ph -09935448449
Email id- dr.stutigupta@gmail.com

Malignant melanoma of the nose and paranasal sinuses is an aggressive disease, typically presenting at an advanced stage, with a 5-year survival rate ranging between 20 and 30%. Melanomas are tumours arising from melanocytes which are neuroectodermally derived cells located in the basal layers of the skin, adnexa and some of the mucosal membranes. Malignant melanomas developing from maxillary sinuses are extremely rare. Their diagnosis can be confirmed by immunohistochemistry by using anti-S100 and HMB-45 antibodies.

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